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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGAP5
All Species:
1.21
Human Site:
T218
Identified Species:
2.96
UniProt:
A6NIR3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NIR3
NP_001137472
663
72983
T218
P
P
T
A
N
T
P
T
P
V
C
K
R
S
M
Chimpanzee
Pan troglodytes
XP_001141446
439
48772
Rhesus Macaque
Macaca mulatta
XP_001082744
804
89081
L333
P
D
K
E
K
K
G
L
E
S
R
A
D
S
I
Dog
Lupus familis
XP_848466
936
102470
D465
T
Y
H
P
S
L
H
D
Y
M
Q
N
V
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXK8
857
94393
D386
T
Y
H
P
S
L
H
D
Y
M
Q
N
V
H
G
Rat
Rattus norvegicus
Q8CGU4
1186
124419
L702
T
L
S
S
N
G
F
L
L
Y
H
P
S
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRL1
864
95088
Q389
P
S
L
H
D
Y
M
Q
N
V
H
G
K
E
I
Zebra Danio
Brachydanio rerio
Q08CI4
339
38765
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NGC3
995
108026
L479
W
K
K
K
Y
V
T
L
C
D
D
G
R
L
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C6C3
776
87784
S249
I
Q
E
F
R
T
Q
S
E
L
D
S
Q
Q
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.6
57.2
49.6
N.A.
52.8
29.5
N.A.
N.A.
N.A.
48.1
22.4
N.A.
30.5
N.A.
N.A.
N.A.
Protein Similarity:
100
64.7
65.9
58.7
N.A.
61.4
38.5
N.A.
N.A.
N.A.
59.2
33.9
N.A.
42.9
N.A.
N.A.
N.A.
P-Site Identity:
100
0
13.3
0
N.A.
0
6.6
N.A.
N.A.
N.A.
13.3
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
20
13.3
N.A.
13.3
20
N.A.
N.A.
N.A.
33.3
0
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% C
% Asp:
0
10
0
0
10
0
0
20
0
10
20
0
10
0
0
% D
% Glu:
0
0
10
10
0
0
0
0
20
0
0
0
0
10
0
% E
% Phe:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
10
0
0
0
0
20
0
0
20
% G
% His:
0
0
20
10
0
0
20
0
0
0
20
0
0
20
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
20
% I
% Lys:
0
10
20
10
10
10
0
0
0
0
0
10
10
0
0
% K
% Leu:
0
10
10
0
0
20
0
30
10
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
10
0
0
20
0
0
0
0
10
% M
% Asn:
0
0
0
0
20
0
0
0
10
0
0
20
0
0
10
% N
% Pro:
30
10
0
20
0
0
10
0
10
0
0
10
0
0
0
% P
% Gln:
0
10
0
0
0
0
10
10
0
0
20
0
10
10
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
10
0
20
0
0
% R
% Ser:
0
10
10
10
20
0
0
10
0
10
0
10
10
20
0
% S
% Thr:
30
0
10
0
0
20
10
10
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
10
0
0
0
20
0
0
20
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
10
10
0
0
20
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _